Self defense doesn't havae to be complicated. In fact, many of the best defenses are simple. The best defense is to not be there. Do not put yourself in situations that could lead to a self-defense scenario. But if you have to fight, then fight.

Soft tissue is the best option. The eyes, throat, ears, and groin are optimal targets in self-defense situations. In self-defense, there is no such thing as fighting dirty.